Gamma Knife Radiosurgery for Neurofibromatosis-II

20 years male from Afghanistan, underwent excision of right CPA SOL in December 13, 2023  insertion of VP shunt in November 27, 2023 presented with complains headache for 6 months, difficulty in walking for 2 & ½ months & loss of right hearing for 1 & ½ months. Patient has no history of radiation & chemotherapy. On clinical examination patient is on wheel chair, right facial palsy, loss of right hearing & ataxia. MRI brain with contrast dated October 29, 2023 shows extra axial enhancing mass lesions seen in bilateral CPA with extension into intra canalicular component suggestive of neurofibromatosis-2. 

Follow up Comparative Study after 6months:

Patient visited the gamma knife center for first routine follow up presented with good resolved  clinical symptoms.Recent MRI brain with contrast dated June 29, 2024 shows significant regression in the targeted Right lesion and sizeable regression in left side when compared with previous MRI brain with contrast dated October 29, 2023 consistent with good ongoing control of lesion.

 

Gamma Knife Radiosurgery for Left Acoustic Schwannoma:

Case Summary:

42 years male, presented with complaints of headache, vertigo, imbalance & slightly decreased left hearing for 1 year. Patient has no history of surgery, chemotherapy and radiation therapy. On clinical examination, patient has slightly decreased left hearing & ataxia. MRI brain with contrast dated May 16, 2023 shows local lesion appearing heterogeneously hyper intense on T2 & flair images noted in left acoustic schwannoma. Audiometry attached. Risks of GKSRS have been explained. Written and valid consent obtained to proceed.

Follow up Comparative Study dated April 2025:

Patient visited the GKSRS center for the first follow up presented with recent MRI Brain with contrast shows significant reduction in targeted SOL  when compared with previous MRI Brain with contrast , consistent with ongoing good tumor control.

 Gamma Knife Radiosurgery For Astrocytoma WHO Grade-II:

Case Summary:

38 years of male, underwent craniotomy for excision of SOL in August 29, 2023 presented with the complaints of fits with loss of consciousness since August 2023 & weakness in left limbs after surgery. Patient has no history of radiation & chemotherapy. On clinical examination, patient has 4/5 power in left limbs. MRI brain with contrast dated September 10, 2023 shows abnormal signal intensity mass seen in right fronto-parietal lesion with post surgical changes. Histopathology dated September 11, 2023 shows Astrocytoma G-II. Risks of GKSRS have been explained. Written and valid consent obtained to proceed.

Follow up Comparative Study After 1 year (April 2025):

Patient consulted Gamma Knife radiosurgery center for first follow up , presented with recent MRI Brain with contrast shows almost complete resolution of targeted lesion when compared with previous MRI Brain with contrast,consistent with ongoing good response to GKSRS Therapy.

 

Gamma Knife Radiosurgery For Right Acoustic Schwannoma.

Case Summary:

40 years lady , presented with complaints of loss of right hearing for 3 months, numbness in tongue & face for 3 months, headache & vertigo for few days. Patient has no history of radiation & chemotherapy. On clinical examination patient has decrease touch sensation in right side of face, loss of right hearing & ataxia. MRI brain with contrast dated December 20, 2023 shows extra axial enhancing abnormal signal intensity mass seen in right CPA with bulges into porus acusticus suggestive of schwannoma. Risks of GKSRS have been explained Written and valid consent obtained to proceed.

Follow up Comparative Study April 16,2025: AFTER ONE YEAR

Patient visited the gamma knife center for the first follow up presented with recent MRI brain dated April 10,2025 shows significant reduction in targeted lesion when compared with previous MRI brain with contrast dated July 06, 2024, consistent with ongoing good control of tumor.

 

GAMMA KNIFE RADIOSURGERY FOR PITUITARY ADENOMA:

Case Summary:

This 49 years male from Quetta, underwent craniotomy & excision of seller SOL in March 30, 2022 presented with complaints of decrease right peripheral vision for 5 months & mild headache for few months. Patient has no history of radiation & chemotherapy. On clinical examination middle aged is sitting on the chair has right temporal field defect. MRI brain with contrast dated May 13, 2022 shows abnormal signal intensity enhancing mass lesion seen in cellar & supra cellar lesion suggestive of adenoma. Perimetry attached & shows field defect on right side. 

Follow up Comparataive Study After 6 months:

Patient visisted the GKSRS centre for the first routine follow up presented with improved clinical symptoms.

Recent MRI brain with contrast shows significant reduction in the targeted SOL , consistent with ongoing tumor control.

Follow up Comparative Study After 1 year:

Patient visisted gamma knife radiosurgery centre for second routine follow up , presented with almost resolved symtoms including good reversal of right temporal field defect.

recent MRI brain with contrast dated November 25,2024 shows further good reduction in targeted SOL only small residual disease seen, with no further growth, consistent with good ongoing response to GKSRS therapy.

 

Gamma Knife Radiosurgery for Craniopharyngioma

Case Summary:

22 years male from Quetta, presented with complaints of headache with nausea for 5 months and blurring of vision for few days. Patient has no history of surgery, radiation & chemotherapy. On clinical examination, patient has blurred vision.

 

Follow up Comparative Study after 6 months:

Patient visited the gamma knife center for the first routine follow up, presented with improved symptoms and good clinical health.

Recent MRI scans dated August 16,2023 shows siginificant reduction in the targeted SOL , consistent with ongoing good response to GKSRS therapy.

Follow up Comparative Study after 1 year:

Patient consulted the GKSRS Clinic with complete resolved symptoms and good health.

Recent MRI scans dated November 25,2024 shows almost complete resolution of targeted SOL with only small residual disease , no further growth , consistenet with good ongoing tumor control.

 

Gamma Knife Radiosurgery for Left Paraganglioma:

32 years female, underwent retro mastoid craniectomy in August 06, 2019 by Dr Farooq Azam presented with complaints of headache for 7 years, loss of left hearing before surgery, facial palsy after surgery & double vision for 1 year. Patient has no history of radiation & chemotherapy. On clinical examination patient has loss of left hearing left facial palsy & right 6^th nerve palsy. MRI brain with contrast dated August 12, 2022 shows large enhancing lesion seen in left side of base of skull at jugular fossa with intra cranial extension & left upper cervical extension & encasement of left internal carotid artery. Histopathology dated August 20, 2019 shows para ganglioma.

 Follow up Comparative Study :

Patient consulted the gamma knife center for the first routine follow up presented with recent MRI Brain with contrast dated October 2023 shows regression in the targeted lesion when compared with previous MRI Brain with contrast dated August 12, 2022 consistent with ongoing control of tumor.